Istituto di Ricerche Farmacologiche «Mario Negri» (IRFMN)

Presentation of the Organisation
Centro Nacional de Investigaciones Cardiovasculares (CNIC)IRFMN is a non profit independent scientific organisation for pharmacological and biomedical research and education founded in 1963 whose aim is to improve the quality of human health and life. Research spans from molecular level to humans through the organisation of large clinical trials in the three main fields: cancer, mental/nervous system disorders and cardiovascular diseases. IRFMN conducts several projects every year for government, national and international organisations including EC. IRFMN has about 900 employees located in 4 different Institutes in Italy.
Department of Cardiovascular Research (IRFMN in Milano)
Main areas of interest include epidemiological aspects of acute myocardial infarction, cardiac failure, cardiac arrhythmias, and clinical and epidemiological investigation of cardiovascular prevention, hypertension and stroke. After successful experience of the GISSI-trials (Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto), the activation of large collaborative networks in the setting of the National Health Service hospitals and in general practice has become a key characteristics of the Department, which can now rely on the permanent collaboration of over 300 clinical groups and of several hundred general practitioners. Firm links have also been established with international leading research groups.

Key people involved
Maria Grazia Franzosi, Biol Sci Dr: Director of the Dept of Cardiovascular Research. Amongst her research interests are methodology and conduction of clinical trials, drug epidemiology, and epidemiology of risk factors for coronary disease. She is member of the Steering Committee of the GISSI Group (Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico, endorsed by the Mario Negri Institute and the National Association of Hospital Cardiologists, ANMCO). She has served on the Steering Committees of several international research networks and has contributed to more than 250 peer-reviewed articles, abstracts, book chapters, and invited publications.
Maria Carla Roncaglioni, Biol Sci Dr: Head of Laboratory for General Practice Research. Amongst other, she gained previous research experience at the Dept. of Biochemistry, Faculty of Medicine, Rijksuniversiteit of Limburg, Maastricht, and at the Cardiovascular Research Unit, Hammersmith Hospital, London. Fields of interest: coordination of multicenter clinical trials and observational studies in different cardiovascular areas. Coordination of a network of more than 1000 GPs involved in epidemiological and experimental studies in the prevention of cardiovascular diseases.
Fausto Avanzini, MD: Head of Coronary Care Unit at Desio Hospital (Milano) since February 1998. Since 1988 he collaborates with the Dept of Cardiovascular Research at IRFMN as clinical advisor. He has coordinated several multicentre clinical studies in the field of cardiovascular diseases in collaboration with the Associazione Nazionale Medici Cardiologi Ospedalieri (AMNCO), General Practitioners’ Associations and the CECOMET (Centro de Epidemiología Comunitaria y Medicina Tropical, Ecuador)
Marta Baviera, Pharm. Dr: Project Manager FOCUS TRIAL, Italy.
Senior Clinical Research Manager at Dept of Cardiovascular Research of IRFMN with years of experience in no-profit clinical trial management. She will coordinate the regulatory aspects, the researchers’ activities and the study monitoring in Italy.
Further Information
http://www.marionegri.it

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Partners
Centro Nacional de Investigaciones Cardiovasculares (CNIC)
Istituto di Richerche Farmacologiche Mario Negri (IRFMN)
Instituto DAMIC (DAMIC)
Fundació Clínic per a la recerca Biomèdica (FCRB)
ARTTIC (ART)
Federación Argentina de Cardiología (FAC)
World Heart Federation (WHF)
Instituto de Salud Carlos III (ISCIII
GRUPO FERRER (FERRER)